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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOX10
All Species:
13.64
Human Site:
S335
Identified Species:
30
UniProt:
P56693
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P56693
NP_008872.1
466
49911
S335
S
G
H
S
A
W
I
S
K
P
P
G
V
A
L
Chimpanzee
Pan troglodytes
Q9BG89
509
56105
G332
A
A
T
P
A
S
A
G
H
V
W
M
S
K
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538379
621
66196
S490
S
G
H
S
A
W
I
S
K
P
P
G
V
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q04888
466
49931
S335
S
G
H
S
A
W
I
S
K
P
P
G
V
A
L
Rat
Rattus norvegicus
O55170
466
50021
S335
S
G
H
S
A
W
I
S
K
P
P
G
V
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519755
494
53531
A363
A
V
A
S
G
H
S
A
W
I
S
K
Q
H
G
Chicken
Gallus gallus
Q9W757
461
49839
W330
A
A
S
G
H
S
A
W
I
S
K
Q
H
G
V
Frog
Xenopus laevis
Q8AXX8
446
49080
L316
S
Y
G
L
T
G
A
L
A
A
G
P
S
A
W
Zebra Danio
Brachydanio rerio
Q6RVD7
245
26782
A115
V
G
G
L
P
A
G
A
L
T
E
S
L
M
S
Tiger Blowfish
Takifugu rubipres
NP_001072112
462
50618
M331
A
W
S
R
K
G
A
M
S
S
S
S
P
S
S
Fruit Fly
Dros. melanogaster
P40657
784
84853
C547
T
V
S
M
A
D
N
C
G
N
L
R
L
S
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.6
N.A.
74.4
N.A.
98.5
97.4
N.A.
64.7
85.1
72.9
23.1
48
22
N.A.
N.A.
N.A.
Protein Similarity:
100
64
N.A.
74.7
N.A.
98.9
98
N.A.
70.2
89.6
79.4
33.4
61.5
33.7
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
6.6
0
13.3
6.6
0
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
100
N.A.
20
13.3
13.3
20
13.3
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
19
10
0
55
10
37
19
10
10
0
0
0
46
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
46
19
10
10
19
10
10
10
0
10
37
0
10
10
% G
% His:
0
0
37
0
10
10
0
0
10
0
0
0
10
10
0
% H
% Ile:
0
0
0
0
0
0
37
0
10
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
37
0
10
10
0
10
0
% K
% Leu:
0
0
0
19
0
0
0
10
10
0
10
0
19
0
37
% L
% Met:
0
0
0
10
0
0
0
10
0
0
0
10
0
10
10
% M
% Asn:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
0
0
0
0
37
37
10
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
10
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
46
0
28
46
0
19
10
37
10
19
19
19
19
19
19
% S
% Thr:
10
0
10
0
10
0
0
0
0
10
0
0
0
0
0
% T
% Val:
10
19
0
0
0
0
0
0
0
10
0
0
37
0
10
% V
% Trp:
0
10
0
0
0
37
0
10
10
0
10
0
0
0
10
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _